We offer a wide range of products and services, including our specialty service, developing Premium Automation Solutions for laboratories to help improve their throughput, efficiency, and reproducibility. We also have a large, dynamic selection of specialized laboratory equipment, as well as more general lab apparatus.
Premium Automation Solutions
Integrating devices to your liquid handling platform can improve your process flow and overall throughput in your lab. ALE has experience integrating devices and are confident in our ability to customize a solution for your needs.Learn More
Installation & Training
Installation and training will help you deliver timely results. Following the manufacturer's installation procedures is imperative for the overall performance of your systems. ALE provides top-quality installation and training, addressing both regulatory and safety concerns.Learn More
Application Development & Service
Providing a total solution from pre-sales evaluation to post-sales support is critical for the success of your lab. The team at ALE is capable of providing first-rate application method templates, hardware, software technical support and service contracts.Learn More
ALE provides tested, reconditioned, and refurbished equipment: reliable products backed by outstanding service.
TECAN M200 Plate Reader
The Tecan Infinite M200 is a user-friendly and affordable multimode reader, designed to cater for the needs of today’s applications. The Infinite 200 can provide a full range of leading detection methods in one easy-to-use modular instrument, with Quad4 monochromator™ . Users can select the desired modules to create the perfect reader for their needs, with the option to upgrade as requirements change. The Infinite M200 offers excellent sensitivity, multiplexing capabilities and high format flexibility, including 6- to 384-well microplates, PCR plates, cuvettes and Tecan’s patented NanoQuant Plate™ for low sample volumes.
As with most multi-mode plate readers, the Tecan M200 is configurable. Please give ALE a call for your desired modes of detection.
ILLUMINA NextSeq DNA Sequencer
A transformative addition to the industry-leading Illumina next-generation sequencing (NGS) system portfolio, the NextSeq Series of systems delivers the power of high-throughput sequencing with the simplicity of a desktop sequencer. Its fast, integrated, sample-to-results workflow enables rapid sequencing of exomes, targeted panels, and transcriptomes in a single run, with the flexibility to switch to lower-throughput sequencing as needed. The systems fit seamlessly into research laboratories, with no need for specialized equipment. Illumina scientists are available at every point along the way with support and guidance, enabling researchers to focus on making the next breakthrough discovery.
The intuitive user interface and load-and-go operation enable researchers to perform more sequencing applications at the highest depth and resolution. It takes less than 10 minutes to load and set up a NextSeq System. While other platforms require several pieces of specialized equipment, the NextSeq Series integrates cluster generation and sequencing into a single instrument and offers a seamless transition for onsite or cloud-based data analysis. After preparation using a simple, streamlined Illumina library prep kit, libraries are loaded into a NextSeq System where sequencing is automated and fast. Data are generated in as little as 12 hours for a 75-cycle sequencing run and less than 30 hours for paired 150-cycle reads. By employing the Illumina industry-leading sequencing by synthesis (SBS) chemistry and file format conventions, the NextSeq Series offers customers access to the broadest ecosystem of established protocols, workflows, data sets, and data analysis tools
ABI 3500xl DNA Sequencer
Applied Biosystems sets a new standard in capillary electrophoresis with the 8-capillary 3500 and 24-capillary 3500xL Genetic Analyzers. The 3500 Series Genetic Analyzers1 are specifically designed to support the demanding performance needs of validated and regulated environments while retaining the unsurpassed application versatility that life science researchers expect from Applied Biosystems.
*8-capillary 3500 System and 24-capillary 3500xL System
*Advanced thermal system design improves temperature control for demanding DNA fragment analysis applications
*Single-line 505 nm, solid-state long-life laser—utilizes a standard power supply; requires no heat removal
*Significantly improved signal uniformity from instrument to instrument, run to run, and capillary to capillary
*Powerful, integrated data collection and primary analysis software provide real-time assessment of data quality
*Radio Frequency Identification (RFID) technology tracks key consumables data and records administrative information
*Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes
*Unrivaled application flexibility—one array and one polymer are used for most applications
*Simple setup, operation, and maintenance—the easiest-to-run, easiest-to-own DNA sequencer to date
ILLUMINA HiSeq 2500 v4 DNA Sequencer
The Illumina HiSeq 2500 v4 has become the undisputed powerhouse of Illumina sequencing systems for high-throughput sequencing applications. To date, millions of samples have been sequenced and thousands of papers have been published utilizing Illumina sequencing technology. With unrivaled data quality, flexible run configurations, and a 10 gigabase (Gb) to 1 terabase (Tb) per run capacity, the HiSeq 2500 has become the production platform of choice for all major Genome Centers and leading institutions around the world.
The HiSeq 2500 System delivers the highest daily throughput and total yield of any individually sold sequencer on the market today. With a massive daily throughput of 160 Gb per day or 1 Tb per run, more samples can be simultaneously sequenced at a greater depth than ever before—producing richer, more meaningful data. Large studies can be completed with reduced hands-on time and reagent cost. In high output mode, the HiSeq 2500 System can process 8 human genomes at 30× coverage or 150 human exomes, assuming 4 Gb per exome at 2 × 75 bp, per run. The HiSeq 2500 System, in high-output mode, is perfect for production scale projects with large genome sizes or studies with hundreds of samples.
BECKMAN COULTER NXP Liquid Handling Automation Workstation
The compact and cost effective Biomek NXP is available with two pipetting models – Multi-channel (96 or 384) or Span 8. Both configurations combine the benefits of a small footprint with the increased efficiency and flexibility of a medium to high throughput instrument. Open-ended flexibility enables integration capability based on your workflow needs.
Biomek NXP features easy-to-use, icon-driven software and a library of ready-to-run methods. Configure the instrument to your specifications and choose from a wide range of components to build your optimal solution:
*Multi-channel (96 or 384) or Span 8 pipetting models
*Precise pipetting from 1 μl - 1000 μl
*360° rotating gripper provides access to from the left and right as well as integrated devices on the back of the instrument
*Open-frame design provides additional workspace for on-deck integrations and storage
*Light curtain pauses instrument operations if a foreign object enters the work area without the loss of data upon restarting a workflow
*Fly-By barcode reader to track sample IDs
*Septum piercing and clot detection
*Heating, cooling and shaking Automated Labware Positioners (ALPs)
ALE provides quality automated platforms, fully serviced and tested per Beckman specifications.
BIOTEK ELx405 Plate Washer
The Biotek ELx405 microplate washers are both efficient and space conscious in all lab settings. The BiotekELx405 platewasher features a patented dual-action manifold to ensure fast operating time and overall cleaning efficiency. Contrary to its small size, the ELx405 plate washer series comes fully loaded with an array of preprogrammed plate washer settings to guarantee optimal performance no matter the microplate type. Among these programs, the ELx405 also employs unique AutoPrime and AutoRinse functions for both speedy maintenance and quick prep times. This Biotek ELx405 microplate washer is in excellent condition and is tested to perform at factory specifications by our technical team at ALE. The pump and bottle set is optional based on lab requirements. Plate Readers Molecular Devices Plate Readers Perkin Elmer
ILLUMINA MiSeq DNA Sequencer
The Illumina MiSeq System offers the first end-to-end sequencing solution, integrating cluster generation, amplification, sequencing, and data analysis into a single instrument. Its small footprint—approximately 2 square feet—fits easily into virtually any laboratory environment. The MiSeq System leverages Illumina sequencing by synthesis technology (SBS), the most widely used, next-generation sequencing chemistry. With over 750 publications to date, the MiSeq System is the ideal platform for rapid and cost-effective genetic analysis.
For results in hours rather than days, the combination of rapid library preparation and the MiSeq System delivers a simple, accelerated turnaround time. Prepare your sequencing library in just 90 minutes with Nextera® library prep reagents, then move to automated clonal amplification, sequencing, and quality-scored base calling in as little as 4 hours on the MiSeq instrument. Sequence alignment can be completed directly on the onboard instrument computer with MiSeq Reporter software or through the BaseSpace platform within 3 hours.
AGILENT Velocity11 Bravo Liquid Handler
The Agilent Bravo Automated Liquid Handling Platform provides precision, unparalleled versatility, and speed in a compact footprint. With seven different, easy-change liquid handling head types, numerous plate pad options, and over 60 on-deck accessories, the Bravo Platform can be customized for a wide range of assays. The unique, open design of the Bravo Platform permits simple integration with other devices for increased throughput when used with robots or the Agilent BenchCel Microplate Handler. The Bravo Platform’s space-saving, nine plate position footprint facilitates biohood placement, enabling liquid transfers for cell-based assays or hazardous reagents. And safety comes standard with the infrared-based, LED safety light curtain provided with all standalone Bravo instruments.
The Bravo Platform is powered by the proven Agilent VWorks Automation Control Software, which features dynamic scheduling, an easy-to-use interface, and innovative error recover technology for instrument control that is adaptable to all types of users.
ALE provides quality services and support for the Agilent Bravo system.
LABCYTE Echo 550 Liquid Handler
Labcyte has revolutionized liquid handling with an innovative technology that produces faster, more accurate results than traditional methods. Whether you are involved in compound management, genomics, proteomics, diagnostics or other laboratory applications, you will do better science and save money with acoustic droplet ejection (ADE).
Powerful but gentle in its approach, ADE drives Labcyte Echo® 500-series Liquid Handlers. It focuses ultrasonic acoustic energy at the meniscus of a fluid sample to eject small droplets of liquid from wells and position them precisely onto a surface suspended above the ejection point.
The Labcyte ECHO 550 is for medium throughput screening and large genomics projects.
ABI 3730xl DNA Sequencer
The Applied Biosystems 3730 Series DNA Analyzers have been developed to meet the growing needs of a broad range of industries and application areas—from core and research laboratories in academic, government, and medical institutions, to biotech, pharmaceutical laboratories, and genome centers. By dramatically improving data quality, significantly reducing total cost per sample, and enabling more runs per day, it allows you to pursue the projects that are important to your laboratory—even those that used to be considered too large, too complicated, or too expensive. New applications demand greater versatility and technical performance from DNA analyzers. Whether your laboratory’s focus is de novo sequencing, resequencing, microsatellite-based fragment analysis, or SNP genotyping, the fully automated 3730 series enables you to work at unprecedented levels of productivity and efficiency.